Condition

Muscle Cramps & Spasms

Medications for muscle cramps, leg cramps, and painful muscle spasms

54 drugs
34 OTC
22 Prescription

Painkiller

NSAID — Non-Steroidal Anti-Inflammatory Drug

3

Topical anti-inflammatory painkiller

NSAID combination

2

Painkiller and anti-inflammatory

NSAID + Analgesic combination

4

Painkiller, Anti-inflammatory, Muscle Relaxant

combination

3

Painkiller and stimulant combination

analgesic

1

Painkiller and fever reducer

analgesic/antipyretic combination

2

Antacid and anti-flatulent combination

Reduces heartburn and gas discomfort

1

Antacid and anti-flatulent

Reduces heartburn and gas discomfort

1

Antacid with anti-flatulent

Reduces heartburn and gas discomfort

2

Antacid

Reduces heartburn and stomach acid pain

3

Mineral and Vitamin Supplement

Helps build strong bones and teeth

1

Muscle Relaxant and Painkiller combination

Relaxes muscles and reduces pain and discomfort

1

Benzodiazepine

sedative/calming medicine

1

Topical painkiller and anti-inflammatory

NSAID-based gel

1

Topical painkiller and anti-inflammatory

NSAID-based

1

Painkiller and Anti-inflammatory

NSAID — Non-Steroidal Anti-Inflammatory Drug

1

Painkiller and anti-inflammatory

NSAID + analgesic combination

1

Painkiller, Anti-inflammatory, and Muscle Relaxant combination

Relieves pain, reduces inflammation, relaxes tense muscles

1

Painkiller, Anti-inflammatory, Muscle Relaxant

Relieves pain, reduces inflammation, relaxes muscles

1

Painkiller / Anti-inflammatory

Relieves pain and reduces inflammation

2

Topical painkiller and anti-inflammatory

NSAID combination

1

Topical anti-inflammatory painkiller

NSAID combination with counterirritants

1

Painkiller and anti-inflammatory with nerve-supporting vitamins

NSAID + Vitamin B complex

1

Antispasmodic

muscle relaxant for cramps

1

Proton Pump Inhibitor

Stomach Acid Reducer

1

Painkiller / Non-Steroidal Anti-Inflammatory Drug

Relieves pain and reduces inflammation

1

Painkiller

analgesic / anti-inflammatory combination

1

Multivitamin and Mineral Supplement with Amino Acid

Helps build strong bones and teeth

1

Antacid and Anti-flatulent

Reduces heartburn and gas discomfort

1

Mineral supplement and anticonvulsant

Helps prevent seizures and replaces minerals in body

1

Topical analgesic and counter-irritant

pain reliever applied on the skin

1

Muscle relaxant

Relaxes muscles and reduces muscle spasms

2

Topical analgesic and counter-irritant

pain-relieving rub

1

Topical analgesic and counter-irritant

pain reliever

1

Muscle relaxant and Painkiller combination

Relaxes muscles and reduces pain

1

NSAID

Non-Steroidal Anti-Inflammatory Drug

1

Antimalarial

Kills parasites that cause malaria

2

Non-Steroidal Anti-Inflammatory Drug

Relieves pain and reduces inflammation

1

Muscle Relaxant

Relaxes tight muscles and reduces spasms

1

When to see a doctor

Seek care if you notice any of the following

  • You experience severe muscle cramps that last for more than an hour and do not respond to treatment.
  • You have difficulty breathing or swallowing due to a severe muscle spasm in your throat or chest.
  • Your muscle cramps or spasms are accompanied by a fever above 38°C (100.4°F) or chills.
  • You have a history of heart problems and experience severe muscle cramps or spasms that may be a sign of a heart attack.
  • Your muscle cramps or spasms are severe enough to cause you to lose control of your bowels or bladder.

For guidance only — always consult a qualified healthcare provider.