Proton Pump Inhibitor (Stomach Acid Reducer)
Last reviewed June 2026
Who is this for?
Omeprazole is a drug that reduces the amount of acid your stomach produces by blocking the tiny pumps in your stomach lining that release acid, giving your stomach and gut time to heal.
Inhibits the H+/K+-ATPase proton pump on gastric parietal cells, irreversibly blocking the final step of gastric acid secretion and reducing intragastric pH to promote ulcer healing and symptom relief.
Available Over The Counter
Get this from any pharmacy or chemist — no prescription needed.
Explore this drug
Take one 20 mg capsule once daily, preferably in the morning before breakfast — swallow it whole with water, do not crush or chew. For severe ulcers, your doctor may increase it to 40 mg daily. A typical course lasts 2 to 8 weeks depending on your condition. Take it at the same time every day for best results.
If you miss a dose, take it as soon as you remember — but if it is almost time for your next dose, skip the missed one and continue as normal. Do not take two capsules at once to make up for it.
Buy only from registered pharmacies — brands like AC-Ome 20, Gastrisafe, Bondpraz, or Cygnus 20 mg are common trusted brands in Nigeria, so avoid unregistered sellers. Do not use omeprazole for more than 2 weeks for simple heartburn without seeing a doctor, as long-term use without supervision can cause problems. If your stomach pain does not improve or gets worse after a few days, see a doctor — it may not just be ordinary ulcer.
Omeprazole can reduce how well clopidogrel (a blood-thinning drug) works, so avoid using them together. It can also affect how your body absorbs ketoconazole and itraconazole (antifungal drugs commonly used in Nigeria). Alcohol can worsen stomach acid problems, so it is best to reduce or avoid alcohol while on this medication.
Check your specific combination
Is it safe to take Omeprazole with your other drugs?
Omeprazole should only be used during pregnancy or breastfeeding if your doctor says it is necessary — consult your doctor before taking it.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it on windowsills or inside hot cars. Keep the capsules in their original pack and away from children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Dispensing Omeprazole?
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