Antihistamine (anti-allergy)
Last reviewed June 2026
Who is this for?
Fexofenadine is an antihistamine that blocks the substance (histamine) your body releases during an allergic reaction. It relieves allergy symptoms without making you feel as sleepy as older allergy medicines.
Blocks H1 histamine receptors in the central and peripheral nervous systems, preventing histamine-mediated allergic symptoms including vasodilation, increased vascular permeability, and pruritus without significant central nervous system penetration due to its large molecular weight and poor blood-brain barrier penetration.
Available Over The Counter
Get this from any pharmacy or chemist — no prescription needed.
Explore this drug
For allergies like sneezing and runny nose: take one 120 mg tablet once daily. For hives and skin itching: take one 180 mg tablet once daily. Swallow the tablet with water. You can take it with or without food, but avoid taking it with fruit juice (like orange or grapefruit juice) as this reduces how well the drug works.
If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue your normal schedule. Do not take two tablets at once to make up for it.
Always buy from a registered pharmacy — avoid roadside sellers or unverified online stores, as fake antihistamines are common. Do not take fruit juice at the same time as this medicine; use plain water instead. If your allergy symptoms do not improve after a few days, see a doctor rather than increasing the dose on your own.
Avoid taking fexofenadine with fruit juices like orange, grapefruit, or apple juice — they reduce how much of the drug your body absorbs. If you take antacids containing aluminium or magnesium (like Gestid or Maalox), wait at least 2 hours before or after taking fexofenadine. Alcohol does not strongly interact with fexofenadine, but it is still wise to limit alcohol as it can worsen dizziness.
Check your specific combination
Is it safe to take Fexofenadine with your other drugs?
Fexofenadine should only be used during pregnancy or breastfeeding if your doctor says it is necessary — consult your doctor before taking it.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in your car or near windows. Keep the tablets in their original pack and always store out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Dispensing Fexofenadine Hydrochloride?
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