Antihistamine and appetite stimulant
Last reviewed June 2026
Who is this for?
Cyproheptadine is an antihistamine that blocks a chemical called histamine in your body, which helps relieve allergic reactions. It also stimulates appetite, which is why many Nigerians know it as an 'appetite booster.'
Blocks H1 histamine receptors to suppress allergic symptoms and inflammatory responses, while simultaneously antagonizing serotonin receptors to stimulate appetite centres in the hypothalamus, promoting weight gain.
Available Over The Counter
Get this from any pharmacy or chemist — no prescription needed.
Explore this drug
Adults usually take one 4 mg tablet 3 times a day, but your doctor may adjust this. You can take it with or without food, but taking it with food can reduce stomach upset. Because it can make you very sleepy, many people prefer to take it at night or avoid driving after taking it.
If you miss a dose, take it as soon as you remember. But if it's almost time for your next dose, just skip the missed one and continue as normal. Don't take a double dose to make up for it.
This drug is widely sold in Nigeria as an appetite booster — do not abuse it or take more than the recommended dose just to gain weight, as overdose can be dangerous. Buy only from licensed pharmacies and look for trusted brands like Apitol, Curegold, or Cypridon — avoid unregistered products from roadside sellers. Do not give this drug to young children to 'make them fat' without a doctor's guidance.
Avoid drinking alcohol while taking cyproheptadine as it will make the drowsiness much worse. Do not combine with other antihistamines like chlorpheniramine (Piriton) as this doubles the sedating effect. Be careful if you are taking sedatives or sleeping tablets, as the combined effect can be dangerous.
Check your specific combination
Is it safe to take Cyproheptadine with your other drugs?
Cyproheptadine is not recommended during pregnancy or breastfeeding — consult your doctor before using it if you are pregnant, planning to become pregnant, or nursing a baby.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be hot, so avoid leaving it in your car or near a window. Keep the container tightly closed and always store out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Dispensing Cyproheptadine Hydrochloride?
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