Antibiotic (Cephalosporin + Beta-lactamase inhibitor combination)
Last reviewed June 2026
Who is this for?
This is a combination antibiotic that pairs cefpodoxime (a cephalosporin antibiotic that kills bacteria) with clavulanic acid (which stops bacteria from resisting the antibiotic). Together, they work harder to fight infections that a regular antibiotic alone might not handle.
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins and preventing peptidoglycan cross-linking; clavulanic acid irreversibly inactivates bacterial beta-lactamases, protecting cefpodoxime from enzymatic degradation and extending spectrum against resistant gram-positive and gram-negative organisms.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
Adults usually take one 325 mg or 625 mg tablet twice daily, depending on the severity of the infection. Take it with food to help your body absorb it better and reduce stomach upset. Swallow the tablet whole with a full glass of water. Always complete the full course your doctor prescribed — even if you feel better after a few days.
If you miss a dose, take it as soon as you remember. But if it's almost time for your next dose, skip the missed one and continue your normal schedule. Never take a double dose to make up for the one you missed.
Important for antibiotics
Always complete the full course even if you feel better. Stopping early can cause the infection to return and become drug-resistant.
Always complete the full antibiotic course your doctor prescribed — stopping early because you feel better can cause the infection to come back stronger and harder to treat. Buy only from licensed pharmacies — brands like Cedoclav, Cefdoclav, Akelox, or Podaxef are available in Nigeria, so avoid unregistered products from roadside sellers. Do not share this medicine with someone else, even if they have similar symptoms — the wrong antibiotic or wrong dose can be dangerous.
Avoid taking with blood thinners like warfarin as it can increase the risk of bleeding. Antacids and ulcer drugs containing aluminium or magnesium can reduce how well the drug works — take them at least 2 hours apart. Avoid alcohol while on this medication as it can worsen side effects like stomach upset and dizziness.
Check your specific combination
Is it safe to take Cefpodoxime with your other drugs?
Do not take this drug during pregnancy or while breastfeeding unless your doctor specifically prescribes it and says the benefit outweighs the risk.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in your car or near a window. Keep the drug in its original pack and far out of the reach of children. If you prepared a suspension, store it in the fridge and use within the number of days stated on the pack.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Dispensing Cefpodoxime; Clavulanic Acid?
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