Condition

Anxiety & Sleep Problems

Medications for anxiety, insomnia, and sleep disorders

17 drugs
1 OTC
16 Prescription

Tricyclic antidepressant

Helps with depression and anxiety symptoms

2

Amitriptyline Hydrochloride

Prescription

Depression, long-lasting nerve pain (neuropathic pain), chronic headaches and migraines, difficulty sleeping linked to depression, bedwetting in children

Amitryptylline HCl TabletsAmyvil 25 TabletJoncine Tablets

Clomipramine Hydrochloride

Prescription

Depression, obsessive-compulsive disorder (OCD — when you have repeated unwanted thoughts or habits you cannot stop), panic attacks, long-lasting anxiety, bed-wetting in children

Aphrodil TabletsClorek-25 Tablet

Benzodiazepine

anti-anxiety medicine

1

Bromazepam

Prescription

Anxiety, nervousness, tension, restlessness, difficulty sleeping due to anxiety, panic attacks

Albetan 1.5mg TabletAlbetan 3mg TabletBromatan 1.5mgBromatan 3mgTalen 1.5mg TabletsTalen 3mg Tablets

Antipsychotic

Phenothiazine

2

Chlorpromazine

Prescription

Mental health conditions like schizophrenia (when someone hears voices or sees things that are not there), severe anxiety and agitation, uncontrollable hiccups, severe nausea and vomiting

Calzim InjectionChlorpromazine TabletsChlorpromazine Tablets BP 100mgHanbet Chlorpromazine InjectionPromedix Chlorpromazine Hydrochloride

Trifluoperazine

Prescription

Mental illness (madness/psychosis), schizophrenia, severe anxiety that doesn't respond to other treatments, agitation, hearing voices or seeing things that are not there

Trifluoperazine Tablets BP 10mgTrifluoperazine Tablets BP 5mg

Benzodiazepine

sedative/calming medicine

1

Diazepam

Prescription

Anxiety and nervousness, trouble sleeping, muscle spasms and stiffness, seizures (convulsions/fits), alcohol withdrawal symptoms, calming patients before surgery or medical procedures

AC-DiazepamAuscel Diazepam 5mg TabletBiozep InjectionCika Diazepam TabletDiazepam InjectionDiazepam TabletEGMP Diazepam Tablets 5mgJarzepam Injection

Antidepressant

SSRI — Selective Serotonin Reuptake Inhibitor

2

Escitalopram

Prescription

Depression, anxiety, panic attacks, excessive worry (generalized anxiety disorder), obsessive-compulsive disorder (OCD)

Ascipram 10 TabletAscipram 20 TabletNeveux Tablets 10mgPromedix Escitalopram

Fluoxetine

Prescription

Depression, anxiety, obsessive-compulsive disorder (when you have repeated unwanted thoughts or habits you cannot control), panic attacks, bulimia (an eating disorder)

Flutex 20mg CapsulesSeroxetine 20 Capsules

Benzodiazepine

sedative/sleeping medicine

1

Flunitrazepam

Prescription

Severe insomnia (inability to sleep), short-term treatment of serious sleeping problems that have not responded to other treatments

AC-FlunitrazepamHypnox TabletsRohypnol 1mg TabletSwinol 1mg Tablets

Antidepressant

Noradrenergic and Specific Serotonergic Antidepressant - NaSSA

1

Mirtazapine

Prescription

Depression, anxiety linked with depression, trouble sleeping caused by depression, poor appetite related to depression

Mirtazapine 15mg TabletsMirtazapine 30mg TabletsMirtazapine 45mg Tablets

Benzodiazepine

sleeping pill/sedative

1

Nitrazepam

Prescription

Difficulty sleeping (insomnia), severe anxiety that prevents sleep

NitrazepamSomnapam TabletSwidon Tablets

Anticonvulsant

Barbiturate

1

Phenobarbital

Prescription

Epilepsy (seizures/convulsions), fits in children, anxiety, difficulty sleeping, status epilepticus (prolonged seizures that won't stop)

Bitalshin 100mg/mL InjectionPhenobarbitone Tablet

Anticonvulsant / Nerve pain medicine

Prevents seizures and relieves nerve pain

1

Pregabalin

Prescription

Nerve pain (especially from diabetes or after shingles), epilepsy (fits/convulsions), body pain from fibromyalgia, anxiety disorder

1980 Pregabalin 150mg CapsulesAGS Pregabalin Capsule IP 300mgCentgesic 300 CapsulesCentgesic 75 CapsulesChevnor Pregabalin Capsules 150mgChevnor Pregabalin Capsules 300mgChevnor Pregabalin Capsules 75mgGabcel 300mg

Antihistamine

sedating

1

Promethazine

OTC

Allergies (sneezing, itching, watery eyes, skin rash), nausea and vomiting, motion sickness (travel sickness), trouble sleeping, cough and cold symptoms

Hanbet Promethazine 50mg InjectionKoyomine TabletPemameth Injection

Antihistamine

also used as anti-nausea and sedative

1

Promethazine Hydrochloride

Prescription

Allergies (sneezing, itching, watery eyes, skin rash), nausea and vomiting, motion sickness (travel sickness), difficulty sleeping, cough and cold symptoms, itchy skin

Bulmethazine Injection 25mg/mLKrisomine SyrupLabzine ElixirMetazine SyrupPetazine Injection

Beta-blocker

heart and blood pressure medicine

1

Propranolol Hydrochloride

Prescription

High blood pressure, fast or irregular heartbeat, chest pain (angina), anxiety and nervousness, trembling or shaking hands, prevention of migraine headaches, overactive thyroid symptoms

Eden Propranolol Hydrochloride 40mgFestpropra TabletPropranolol 40 TabletPropranolol TabletsTimec Propranolol Tablets

Sedative-Hypnotic

sleeping pill

1

Zopiclone

Prescription

Short-term treatment of difficulty sleeping (insomnia), trouble falling asleep, waking up too early, waking up several times during the night

Nitress TabletsZopice Tablet

When to see a doctor

Seek care if you notice any of the following

  • If you experience chest pain or tightness, especially if it spreads to your arms, neck, or jaw, go to your nearest clinic or hospital immediately.
  • If you have severe difficulty breathing, such as feeling like you're choking or can't catch your breath, seek medical help right away.
  • If you notice changes in your mood, such as feeling extremely irritable, aggressive, or suicidal, go to your nearest clinic or hospital as soon as possible.
  • If you experience severe dizziness or lightheadedness that makes it hard to stand or walk, go to your nearest clinic or hospital for immediate attention.
  • If you have trouble speaking or swallowing, or if you experience numbness or weakness in your face, arms, or legs, go to your nearest clinic or hospital as soon as possible.

For guidance only — always consult a qualified healthcare provider.