Antidiabetic (DPP-4 inhibitor)
Last reviewed June 2026
Who is this for?
Teneligliptin is a diabetes medicine that works by helping your body produce more insulin after meals and reducing the amount of sugar your liver releases into your blood, so your blood sugar stays at a healthy level.
Inhibits dipeptidyl peptidase-4 (DPP-4), preventing degradation of incretin hormones (GLP-1 and GIP) and thereby increasing insulin secretion and reducing glucagon levels in response to meals.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
Take one 20mg tablet once a day, with or without food. It is usually taken at the same time every day. Your doctor may increase the dose to 40mg once daily if your blood sugar is not well controlled. Do not change your dose without your doctor's advice.
If you miss a dose, take it as soon as you remember on the same day. If it is almost time for your next dose, skip the missed one and continue your normal schedule. Do not take two tablets at once to make up for a missed dose.
Only buy from licensed pharmacies — teneligliptin sold as Tenelisign Tablets should come in proper packaging, not loose tablets from roadside sellers. Monitor your blood sugar regularly as your doctor advises, especially during the harmattan season or when you are fasting. Do not share this medicine with anyone else even if they also have diabetes, as dosing must be personalised by a doctor.
Be careful when taking teneligliptin with other diabetes medicines like glimepiride or insulin, as the combination can cause your blood sugar to drop too low. Some heart medicines and antibiotics can affect how teneligliptin works, so always tell your doctor about all your medicines. Drinking alcohol can make blood sugar control harder and increase the risk of low blood sugar.
Check your specific combination
Is it safe to take Teneligliptin with your other drugs?
Teneligliptin is not recommended during pregnancy or breastfeeding — consult your doctor for a safer alternative if you are pregnant, planning to become pregnant, or nursing a baby.
Store in a cool, dry place away from direct sunlight and heat — this is important in Nigerian weather. Keep the tablets in their original packaging and away from moisture. Always keep out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.