Phosphodiesterase-5 (PDE5) Inhibitor and Selective Serotonin Reuptake Inhibitor (SSRI) — for erectile dysfunction and premature ejaculation
Last reviewed June 2026
Who is this for?
This is a combination drug containing Tadalafil and Dapoxetine — Tadalafil helps increase blood flow to the penis to achieve and maintain an erection, while Dapoxetine helps delay ejaculation so you can last longer during sex.
Inhibits phosphodiesterase-5 enzyme in corpus cavernosum, increasing cGMP levels and promoting penile smooth muscle relaxation and vasodilation for erectile function; concurrently inhibits serotonin reuptake in the central nervous system, increasing synaptic serotonin concentration to delay ejaculation.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
Take one tablet (usually 20 mg Tadalafil/30 mg Dapoxetine) by mouth with a full glass of water, about 1 to 3 hours before sexual activity. You can take it with or without food, but avoid heavy or fatty meals as they may slow the effect. Do not take more than one tablet in 24 hours. Common brands in Nigeria include Senegra Tablet, Sengra Forte, and Tadalis Plus.
This drug is not taken on a daily schedule — you only take it when you plan to have sex. So there is no missed dose to worry about. Just never take two tablets to make up for anything.
Buy only from licensed pharmacies — avoid roadside vendors or market sellers as fake versions of this drug are very common in Nigeria. Do not share this medication with friends even if they have similar problems, as it may not be safe for them. If you feel dizzy after taking it, do not drive okada, keke, or any vehicle.
Do NOT take with nitrate drugs used for chest pain or heart problems (like isosorbide or nitroglycerin) as this can cause a dangerous drop in blood pressure. Avoid drinking alcohol as it increases the risk of dizziness, fainting, and low blood pressure. Do not combine with other drugs for erection problems like Sildenafil (Viagra) or blood pressure medications without your doctor's approval.
Check your specific combination
Is it safe to take Tadalafil; with your other drugs?
This drug is only for adult men and should never be taken by women, whether pregnant, breastfeeding, or otherwise.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so don't leave it in your car or near a window. Keep it in its original packaging and far away from children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Dispensing Tadalafil; Dapoxetine?
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