Alpha-1 blocker (prostate medicine)
Last reviewed June 2026
Who is this for?
Silodosin is a medicine that relaxes the muscles around the prostate gland and the opening of the bladder, making it easier for men to urinate. It works by blocking certain receptors (called alpha-1 receptors) in the prostate, which helps urine flow more freely.
Selectively blocks alpha-1A adrenergic receptors in the prostate and bladder neck, reducing smooth muscle contraction and improving urinary flow in benign prostatic hyperplasia. This receptor selectivity minimizes effects on vascular alpha-1B receptors, resulting in minimal blood pressure reduction compared to non-selective alpha-blockers.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
Take one 8 mg capsule once daily with food — preferably with the same meal each day. Swallow the capsule whole with water; do not crush, chew, or open it. Taking it with food helps your body absorb it properly. If your doctor finds you have kidney problems, the dose may be reduced to 4 mg once daily.
If you miss a dose, skip it and take your next dose at the usual time with your meal. Do not take two capsules at once to make up for the missed one.
Always buy from a reputable pharmacy — avoid roadside sellers or unregistered shops, as fake medicines are common. Stand up slowly from sitting or lying down to avoid dizziness and falls, especially in the first few days. If you are scheduled for cataract or eye surgery, inform your eye doctor that you are taking silodosin, as it can affect the procedure.
Do not take silodosin with other prostate or blood pressure medicines like tamsulosin, prazosin, or doxazosin — combining them can cause a dangerous drop in blood pressure. Avoid taking it with strong antifungal medicines like ketoconazole or itraconazole, as they increase silodosin levels in your blood. Alcohol can worsen dizziness and lightheadedness, so limit or avoid alcohol while on this medicine.
Check your specific combination
Is it safe to take Silodosin with your other drugs?
Silodosin is only for men and should never be taken by women, whether pregnant, breastfeeding, or otherwise.
Store in a cool, dry place below 30°C — away from direct sunlight and humidity, which can be a problem in Nigerian weather. Keep the capsules in their original packaging and always store out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Dispensing Silodosin?
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