Bronchodilator and Antihistamine combination
Last reviewed June 2026
Who is this for?
This is a combination medicine containing three active ingredients: Salbutamol (opens up the airways in your lungs), Theophylline (relaxes the muscles around your airways to help you breathe easier), and Chlorphenamine (an antihistamine that reduces allergic reactions like sneezing and runny nose). Together, they work to relieve breathing difficulties caused by asthma and allergies.
Activates beta-2 adrenergic receptors in bronchial smooth muscle, causing bronchodilation and improved airflow, while inhibiting phosphodiesterase to increase cyclic AMP levels for sustained bronchial relaxation. Blocks H1 histamine receptors to reduce allergic-mediated bronchoconstriction, mucus secretion, and inflammatory mediator release.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
Adults usually take 1 tablet two or three times daily. You can take it with or without food, but taking it with food can help reduce stomach upset. Swallow the tablet whole with a glass of water. Follow your doctor's instructions on how long to use it.
If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue with your normal schedule. Do not take two doses at once to make up for it.
Buy only from reputable pharmacies — avoid buying from roadside sellers or open markets as the medicine may be fake or expired. Do not use this medicine to replace your inhaler during a severe asthma attack — if your breathing suddenly gets worse, seek emergency care. Do not drive or operate heavy machines after taking this medicine as Chlorphenamine can make you very drowsy.
Avoid drinking coffee, kola nut, or other caffeine-containing drinks as they can increase the side effects of Theophylline like fast heartbeat and shakiness. Alcohol can make the drowsiness from Chlorphenamine much worse — avoid it. If you are taking medicines for high blood pressure (like propranolol or atenolol), they may reduce how well this drug works — inform your doctor.
Check your specific combination
Is it safe to take Salbutamol with your other drugs?
This combination is not recommended during pregnancy or breastfeeding unless your doctor specifically prescribes it — consult your doctor before use.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid storing near windows or in your car. Keep the medicine in its original container and always keep it out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.