Antibiotic (Rifamycin)
Last reviewed June 2026
Who is this for?
Rifampicin is a strong antibiotic that works by killing bacteria and stopping them from multiplying — it does this by blocking the bacteria's ability to make the proteins they need to survive.
Binds to bacterial RNA polymerase, inhibiting transcription and RNA synthesis, leading to disruption of bacterial protein production and cell death.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
For TB, the usual adult dose is 450mg to 600mg once daily (typically 600mg if you weigh 50kg or more). Take it on an empty stomach — at least 30 minutes before food or 2 hours after eating — with a full glass of water. Your doctor will tell you the exact dose and how long to take it, which is usually several months.
If you miss a dose, take it as soon as you remember. But if it's almost time for your next dose, skip the missed one and continue your normal schedule. Never take two doses at once to make up for it.
Important for antibiotics
Always complete the full course even if you feel better. Stopping early can cause the infection to return and become drug-resistant.
Always complete the full TB treatment course even if you feel better — stopping early can cause drug-resistant TB which is much harder and more expensive to treat. Only buy from licensed pharmacies — products like Rifalab Forte Caplets should come in proper packaging with expiry dates. Do not share your rifampicin with anyone else, even if they have similar symptoms.
Rifampicin reduces the effectiveness of birth control pills — use an additional method like condoms while on treatment. It also reduces the effect of HIV drugs (antiretrovirals), so your doctor must adjust doses. Avoid alcohol completely, as combining it with rifampicin greatly increases the risk of liver damage.
Check your specific combination
Is it safe to take Rifampicin with your other drugs?
Rifampicin should only be used during pregnancy or breastfeeding if your doctor decides the benefit outweighs the risk — always consult your doctor before taking it.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it on windowsills or in cars. Keep the container tightly closed to protect from humidity, and always keep it out of children's reach.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.