Antispasmodic and Painkiller combination
Last reviewed June 2026
Who is this for?
This is a combination drug containing three active ingredients — pitofenone (a muscle relaxant that eases muscle spasms in your stomach and intestines), fenpiverinium (which helps reduce cramping by blocking certain nerve signals), and acetaminophen (a painkiller and fever reducer also known as paracetamol). Together, they work to relieve pain and spasms in your belly and internal organs.
Blocks smooth muscle contraction by inhibiting phosphodiesterase and calcium influx (pitofenone and fenpiverinium), while acetaminophen inhibits prostaglandin synthesis via COX inhibition, together providing antispasmodic and analgesic effects for visceral pain relief.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
Adults typically take 1 to 2 tablets up to 3 times a day, preferably after food to reduce stomach upset. Swallow the tablet whole with a glass of water. Do not take more than 6 tablets in 24 hours. This medicine is commonly sold as Regalgan Tablets in Nigeria.
If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue as normal. Do not take a double dose to make up for the one you missed.
Do not combine Regalgan with other paracetamol products — many Nigerian drugs contain paracetamol, so check the label to avoid overdose. Buy only from licensed pharmacies, not from roadside vendors or open markets where storage conditions are poor. If your pain does not improve after a few days, see a doctor rather than increasing the dose on your own.
Avoid drinking alcohol while taking this medicine, as it increases the risk of liver damage from the paracetamol and can worsen dizziness. Do not combine with other paracetamol-containing drugs (like Panadol or other cold remedies) to avoid overdose. Be careful if you are already taking sedatives, sleeping pills, or other drugs that cause drowsiness.
Check your specific combination
Is it safe to take Pitofenone with your other drugs?
Do not take this drug during pregnancy or while breastfeeding unless your doctor specifically tells you it is safe — consult your doctor first.
Store in a cool, dry place away from direct sunlight and heat — this is especially important in Nigeria's hot climate. Keep the tablets in their original packaging and always store out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.