Decongestant
Last reviewed June 2026
Who is this for?
Phenylephrine hydrochloride is a decongestant that works by narrowing the blood vessels in your nose and sinuses to reduce swelling and open up blocked airways so you can breathe more easily.
Activates α1-adrenergic receptors on nasal blood vessels, causing vasoconstriction and reducing mucosal edema to relieve nasal congestion. This sympathomimetic action decreases blood flow to nasal tissues, allowing improved airflow through congested passages.
Available Over The Counter
Get this from any pharmacy or chemist — no prescription needed.
Explore this drug
For adults, the usual dose is 10 mg (one tablet) every 4 to 6 hours as needed, but do not take more than 4 doses (40 mg) in 24 hours. You can take it with or without food. It is usually used for short-term relief — do not use continuously for more than 7 days without seeing a doctor.
Since this medicine is usually taken only when you have symptoms, there is no strict schedule. If you forget a dose, simply take it when you remember, but do not double up. Make sure you wait at least 4 hours before taking another dose.
Do not use this drug for more than 7 days straight — if your congestion has not cleared, see a doctor. Buy only from reputable pharmacies, not roadside sellers, as fake drugs are common in Nigeria. Check the expiry date and packaging carefully, especially for brands like Realflex.
Do not take with MAO inhibitor drugs (some medicines used for depression) as this combination can cause a dangerous spike in blood pressure. Avoid combining with other decongestants or cold medicines that already contain phenylephrine to prevent overdose. Limit or avoid alcohol as it can worsen dizziness and drowsiness.
Check your specific combination
Is it safe to take Phenylephrine with your other drugs?
Pregnant and breastfeeding women should consult their doctor before taking phenylephrine, as it may not be safe for the baby.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it on windowsills or in your car. Keep the container tightly closed to protect from humidity and always keep it out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.