ACE Inhibitor (blood pressure medicine)
Last reviewed June 2026
Who is this for?
Perindopril arginine is a blood pressure-lowering medicine (ACE inhibitor) that works by relaxing your blood vessels so blood can flow more easily, reducing the workload on your heart.
Inhibits angiotensin-converting enzyme (ACE), preventing conversion of angiotensin I to angiotensin II and reducing systemic vasoconstriction, aldosterone secretion, and sodium retention. This results in vasodilation, decreased peripheral vascular resistance, and reduced blood pressure.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
Take one tablet once a day in the morning, before food. The usual starting dose is 5 mg (one Coversyl 5 mg tablet), and your doctor may increase it to 10 mg daily depending on how your body responds. Swallow the tablet whole with a glass of water.
If you miss a dose, skip it and take your next dose at the usual time the following morning. Do not take two tablets at once to make up for the missed one.
Only buy Coversyl or perindopril from a licensed pharmacy — do not buy from roadside vendors or open markets, as fake versions are common. Do not stop taking this medicine suddenly because your blood pressure feels fine — high blood pressure is a silent killer and needs ongoing treatment. Do not share your prescription with someone else who has high blood pressure, as doses must be individually determined by a doctor.
Avoid using potassium supplements or salt substitutes that contain potassium while on this drug, as it can raise potassium to dangerous levels. NSAIDs like ibuprofen (common in Nigeria for body pain) can reduce the effectiveness of perindopril and harm your kidneys. Alcohol can increase the blood pressure-lowering effect and make you feel very dizzy or faint.
Check your specific combination
Is it safe to take Perindopril with your other drugs?
Do NOT take perindopril if you are pregnant or planning to become pregnant — it can seriously harm or kill your unborn baby; also avoid it while breastfeeding, and talk to your doctor about a safer alternative.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in your car or near windows. Keep the tablets in their original container and far out of children's reach.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
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