Insulin (long-acting and rapid-acting combination)
Last reviewed June 2026
Who is this for?
Ryzodeg is an injectable insulin that combines two types of insulin — one that works all day long (degludec) and one that works fast after meals (aspart) — to help control blood sugar levels in people with diabetes.
Binds to insulin receptors on muscle, fat, and liver cells, activating glucose uptake and utilisation while suppressing hepatic glucose production and lipolysis; insulin degludec provides sustained basal glycaemic control while insulin aspart enables rapid postprandial glucose reduction.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
This is an injection given under the skin (not into a vein), usually once or twice daily with your main meal(s). Your doctor will decide the exact dose based on your blood sugar readings. Use the Ryzodeg FlexTouch pen as shown by your doctor or pharmacist — inject into your belly, upper arm, or thigh, and rotate the injection spot each time.
If you miss your dose at a meal, take it with your next main meal that day, then go back to your normal schedule. Never take a double dose to make up for a missed one. If you are unsure, check your blood sugar and call your doctor.
Always buy Ryzodeg from a licensed pharmacy — never buy insulin from roadside sellers or unregistered shops, as it may have been stored in heat and lost its effectiveness. Learn to recognize the signs of low blood sugar (shaking, sweating, confusion) and always carry sugar, sweets, or a sugary drink with you. Do not share your insulin pen with anyone, even if you change the needle — this can spread infections.
Some blood pressure medicines (like beta-blockers such as atenolol) can hide the signs of low blood sugar, making it harder to know when your sugar drops. Drinking alcohol can cause dangerous drops in blood sugar when using insulin. Some diabetes tablets like glimepiride or metformin may increase the effect of insulin, so your doctor needs to adjust doses carefully.
Check your specific combination
Is it safe to take Insulin with your other drugs?
If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before using Ryzodeg — your insulin needs may change during pregnancy and your doctor will need to monitor and adjust your dose.
Before first use, store in a refrigerator (2°C to 8°C) — not in the freezer. Once in use, keep the pen at room temperature (below 30°C) for up to 21 days. Do not expose to direct sunlight or extreme heat, which is common in Nigeria. Keep the cap on when not in use and always keep away from children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.