Topical corticosteroid (anti-inflammatory steroid)
Last reviewed June 2026
Who is this for?
Hydrocortisone acetate is a mild steroid (corticosteroid) cream or ointment that works by reducing swelling, redness, and itching on the skin.
Binds to glucocorticoid receptors in the cytoplasm, translocating to the nucleus to suppress pro-inflammatory gene expression and reduce production of inflammatory mediators (cytokines, chemokines, and adhesion molecules), thereby decreasing local inflammation, erythema, and pruritus.
Available Over The Counter
Get this from any pharmacy or chemist — no prescription needed.
Explore this drug
For the cream or ointment, apply a thin layer to the affected area 1 to 3 times daily and rub in gently. Do not cover the area with a bandage unless your doctor tells you to. Use only the amount needed and stop once the condition clears up — do not use for more than 7 days without seeing a doctor.
If you forget to apply it, use it as soon as you remember. If it is almost time for your next application, just skip the missed one and continue as normal. Do not apply double the amount to make up for it.
Do not use hydrocortisone acetate cream as a skin-lightening or toning cream — this is dangerous and can permanently damage your skin. Buy only from licensed pharmacies and look for trusted brands like PKN Hydrocortisone Acetate Cream. Do not use for longer than one week without a doctor's guidance, even if the cream is helping.
Avoid using other steroid creams or medicated skin products on the same area at the same time unless your doctor says so. Be cautious using it alongside skin-lightening or toning creams that already contain steroids, as this can cause serious skin damage.
Check your specific combination
Is it safe to take Hydrocortisone with your other drugs?
Do not use hydrocortisone acetate cream during pregnancy or breastfeeding without consulting your doctor first, especially avoid applying it on the breasts if breastfeeding.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in a car or near a window. Keep the tube tightly closed and out of the reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
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