Anticancer (BRAF kinase inhibitor)
Last reviewed June 2026
Who is this for?
Encorafenib (sold as Braftovi) is a cancer medicine that works by blocking a faulty protein called BRAF in cancer cells, which helps slow down or stop the growth of certain types of cancer.
Inhibits BRAF V600E kinase, a mutated protein that drives uncontrolled cell division in melanoma and colorectal cancers, thereby suppressing the MAPK signaling pathway and inducing apoptosis in BRAF-mutant malignant cells.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
The usual adult dose is 450 mg once daily (for example, six 75 mg capsules) when used with another cancer drug called binimetinib, or 300 mg once daily when used with cetuximab for colon cancer. Swallow the capsules whole with water — do not open, crush, or chew them. You can take it with or without food. Take it at the same time every day as your doctor directs.
If you miss a dose by more than 12 hours, skip it and take your next dose at the regular time. Do not take two doses at once to make up for the missed one.
This is a highly specialised cancer drug — only use it as prescribed by a qualified cancer specialist (oncologist). Do not buy from unverified sources or roadside sellers, as fake cancer drugs are very dangerous. Attend all your follow-up appointments so your doctor can monitor your blood, skin, and overall health closely.
Avoid grapefruit and grapefruit juice as they can increase the drug level in your blood and cause more side effects. Some antibiotics and antifungal medicines (like ketoconazole or rifampicin) can strongly affect how this drug works — always tell your doctor about every medicine you are taking. Avoid alcohol as it can worsen side effects like nausea and tiredness.
Check your specific combination
Is it safe to take Encorafenib with your other drugs?
Encorafenib can harm an unborn baby — do not take it if you are pregnant or breastfeeding, and use effective contraception during treatment and for at least 2 weeks after your last dose.
Store in a cool, dry place below 30°C — away from direct sunlight and humidity, which can be a challenge in Nigeria. Keep the capsules in their original container and always keep them far out of the reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Dispensing Encorafenib?
Clinical tools built for Nigerian pharmacists — launching soon.