Antiretroviral (ARV) — HIV medication
Last reviewed June 2026
Who is this for?
This is a combination tablet containing three antiretroviral (anti-HIV) medicines — Dolutegravir, Lamivudine, and Tenofovir — that work together to stop the HIV virus from multiplying in your body, helping your immune system stay strong.
Inhibits HIV replication through three complementary mechanisms: Dolutegravir blocks HIV integrase, preventing viral DNA integration into the host genome; Lamivudine and Tenofovir are nucleoside/nucleotide reverse transcriptase inhibitors that suppress reverse transcription of viral RNA into DNA. Together, these agents reduce viral load and preserve CD4+ T-cell count.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
Take one tablet once a day, at the same time every day. You can take it with or without food. Do not break or crush the tablet — swallow it whole with water. Consistency is very important, so try to never skip a day.
If you remember the same day, take it as soon as you can. If it is almost time for your next dose, skip the missed one and continue your normal schedule. Never take two tablets at once to make up for a missed dose.
Always buy from a licensed pharmacy — do not purchase ARV drugs from roadside vendors or unverified online sellers, as fake HIV drugs are dangerous and common. Never share your HIV medication with anyone else, even if they are also HIV-positive, because dosing and drug combinations differ. Take this medicine every single day without stopping — skipping doses can cause the virus to become resistant, making your treatment stop working.
Do not take this medicine with other drugs that already contain Lamivudine or Tenofovir (like some hepatitis B medicines), as you may accidentally double the dose. Avoid taking it at the same time as antacids, calcium, or iron supplements — take those at least 6 hours apart or 2 hours after your HIV tablet. Alcohol can put extra stress on your liver, so limit or avoid drinking while on this medication.
Check your specific combination
Is it safe to take Dolutegravir with your other drugs?
This combination can be used during pregnancy and breastfeeding under a doctor's guidance — your doctor will weigh the benefits against any risks and monitor you closely.
Store in a cool, dry place below 30°C — away from direct sunlight and humidity. Keep in the original container with the lid tightly closed. Store well out of reach of children. Do not keep in the bathroom or near a window where heat builds up.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Dispensing Dolutegravir; Lamivudine; Tenofovir Disoproxil Fumarate?
Clinical tools built for Nigerian pharmacists — launching soon.