Prescription

Topical corticosteroid (very potent steroid skin cream)

Clobetasol Propionate

Last reviewed April 2026

Who is this for?

What is this drug?

Clobetasol propionate is a very strong steroid cream or lotion that works by reducing swelling, redness, and itching on the skin — it calms down your body's reaction that causes skin irritation.

What is it used for?

Stubborn skin rasheseczema (dry itchy skin)psoriasis (thick scaly patches on skin)severe skin allergiesskin inflammation that has not responded to milder creams

Prescription Required

A doctor's prescription is required to obtain this drug legally.

Quick Interaction Check

Is Clobetasol safe to take with another drug?

Check with multiple drugs →