Integrase inhibitor (Antiretroviral)
Last reviewed June 2026
Who is this for?
Cabotegravir is an HIV medication that works by blocking an enzyme called integrase, which the HIV virus needs to multiply in your body. It is available in Nigeria under the brand name Apretude, either as tablets or as a long-acting injection.
Inhibits HIV integrase enzyme, preventing integration of viral DNA into the host genome and blocking viral replication. When used as PrEP, it establishes protective concentrations in blood and tissues to prevent establishment of infection following HIV exposure.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
For HIV prevention with tablets: Take one 30 mg tablet once daily by mouth, with or without food. The tablets are usually taken for about one month before switching to the long-acting injection. For the injection: Your healthcare provider will give you a 600 mg injection into your buttock muscle — first two injections are one month apart, then every two months after that. Do not try to inject yourself at home.
If you miss a tablet dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one and continue your normal schedule — do not double up. If you miss an injection appointment, contact your healthcare provider as soon as possible to reschedule, because gaps in protection can increase your risk of getting HIV.
Only get Apretude from a licensed pharmacy or hospital — do not buy from roadside sellers or unverified online stores, as fake HIV medicines are dangerous. If you are using cabotegravir for HIV prevention, you must get tested for HIV regularly because using it while unknowingly HIV-positive can lead to drug resistance. Do not share this medication with others even if they also want HIV protection — each person needs their own prescription and proper medical follow-up.
Rifampicin (commonly used for tuberculosis treatment in Nigeria) greatly reduces how well cabotegravir works — do not use them together. Carbamazepine and phenytoin (used for seizures/convulsions) can also reduce its effectiveness. Always tell your doctor about every medicine you are taking, including herbal remedies.
Check your specific combination
Is it safe to take Cabotegravir with your other drugs?
Cabotegravir is not well-studied in pregnant or breastfeeding women — consult your doctor before using it if you are pregnant, planning to become pregnant, or breastfeeding.
Store tablets at room temperature, away from direct sunlight and heat. In hot Nigerian weather, do not leave the medicine in your car or near a window. Keep in a cool, dry place and always out of the reach of children. The injection is stored and handled by your healthcare provider.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Dispensing Cabotegravir?
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