Anti-glaucoma (Carbonic Anhydrase Inhibitor + Beta-Blocker combination)
Last reviewed June 2026
Who is this for?
Brinzolamide/Timolol (sold as Azarga in Nigeria) is an eye drop that combines two medicines which work together to reduce pressure inside the eye by slowing down the production of fluid in the eye and helping it drain better.
Inhibits carbonic anhydrase II in the ciliary body, reducing aqueous humour production, whilst simultaneously blocking beta-1 adrenergic receptors to further decrease aqueous humour secretion and increase uveoscleral outflow, thereby lowering intraocular pressure.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
Shake the bottle well before use. Put one drop in the affected eye(s) twice a day, usually morning and evening. Gently close your eye after putting in the drop and press lightly on the inner corner of your eye near your nose for about 1-2 minutes to stop the medicine from draining away. If you use other eye drops, wait at least 5 minutes between each one.
If you miss a dose, put in the drop as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue your normal schedule. Do not put in a double dose to make up for the one you missed.
Only buy Azarga from a licensed pharmacy — fake or expired eye drops from roadside sellers can damage your eyes permanently. Do not share your eye drops with anyone else as this can spread infection. Keep all your eye clinic appointments so the doctor can check if the pressure in your eye is well controlled.
Other blood pressure or heart medicines (especially calcium channel blockers like amlodipine) can cause dangerously low heart rate when combined with this eye drop. Oral carbonic anhydrase inhibitors like acetazolamide (Diamox) should not be used together with this medicine as it can increase side effects. Tell your doctor about all medicines you are currently taking.
Check your specific combination
Is it safe to take Brinzolamide; with your other drugs?
This medicine is not safe during pregnancy or breastfeeding — consult your doctor before using it, as timolol can pass into breast milk and may harm the baby.
Store below 30°C in a cool, dry place away from direct sunlight and heat — this is important in Nigeria's hot climate. Keep the bottle tightly closed when not in use. Keep out of the reach of children. Once opened, use within 4 weeks and throw away any leftover medicine after that.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Dispensing Brinzolamide; Timolol?
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