Question 1

What is Artesunate used for?

Accepted Answer

Severe malaria, uncomplicated malaria (usually combined with another antimalarial drug)

Question 2

How do you take Artesunate?

Accepted Answer

For severe malaria, artesunate injection is given by a doctor or nurse in a hospital — you cannot self-administer this. The usual adult dose is 2.4 mg per kg body weight given intravenously at 0 hours, 12 hours, 24 hours, then once daily until you can swallow tablets, after which you switch to an oral antimalarial to complete treatment. The rectal capsule (Artecap) may be used as emergency pre-referral treatment before reaching a hospital.

Question 3

What are the side effects of Artesunate?

Accepted Answer

Nausea or vomiting, dizziness or headache, loss of appetite, body weakness or tiredness, dark-coloured urine (this can happen a week or two after treatment and should be reported to your doctor)

Question 4

Who should not take Artesunate?

Accepted Answer

People who are allergic to artesunate or any artemisinin-based drug. Women in the first trimester of pregnancy unless it is a life-threatening situation. People with known severe allergic reactions to any ingredient in the injection or rectal capsule.

Question 5

Is Artesunate safe during pregnancy?

Accepted Answer

Artesunate can be used in the second and third trimester of pregnancy for severe malaria when the mother's life is at risk, but should be avoided in the first trimester unless there is no safer alternative — always let your doctor decide. Breastfeeding mothers should consult their doctor.

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