Carbonic anhydrase inhibitor (diuretic/water tablet)
Last reviewed June 2026
Who is this for?
Acetazolamide is a medicine that works by reducing the amount of fluid your body produces in certain areas like the eyes and brain — it does this by blocking an enzyme called carbonic anhydrase, which helps control fluid and acid balance in your body.
Inhibits carbonic anhydrase enzyme in the kidney proximal tubule and eye ciliary body, reducing bicarbonate reabsorption and aqueous humour production, thereby decreasing intraocular pressure and promoting diuresis. Additionally, raises cerebrospinal fluid pH and alters neuronal excitability, reducing seizure threshold and preventing high-altitude cerebral oedema.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
For glaucoma, the usual adult dose is 250 mg (1 tablet) taken 1 to 4 times daily, as your doctor prescribes. For epilepsy, 250 mg to 1000 mg daily in divided doses. Take it with food or a full glass of water to reduce stomach upset. Follow your doctor's exact instructions — dosing depends on your condition.
If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue your regular schedule. Do not take a double dose to make up for the one you missed.
This is a prescription-only medicine — do not buy it from roadside sellers or self-medicate, as wrong use can cause serious kidney problems. Drink plenty of water while taking this drug to reduce the risk of kidney stones. If you notice unusual tiredness, confusion, or muscle cramps, see your doctor quickly as it could mean your body salts are too low.
Aspirin or other high-dose painkillers can increase the risk of serious side effects when taken with acetazolamide. Metformin (used for diabetes/sugar) — acetazolamide may affect how well it works. Avoid alcohol as it can worsen dizziness and drowsiness from this medicine.
Check your specific combination
Is it safe to take Acetazolamide with your other drugs?
Acetazolamide is not considered safe during pregnancy as it may harm the unborn baby, and it passes into breast milk — do not use it if you are pregnant or breastfeeding unless your doctor specifically says so.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in your car or near windows. Keep it in its original container and far away from children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Dispensing Acetazolamide?
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